SIGNAL // LOADING
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Glossary term
Contraindication
A specific reason a pathway is off the table - either hard (absolute) or conditional (relative).
Contraindications are conditions, histories, or medications that make a specific pathway unsafe. Absolute contraindications rule the pathway out entirely - MTC or MEN2 for GLP-1, active estrogen-receptor-positive breast cancer for HRT, acute pancreatitis for GLP-1. Relative contraindications demand extra monitoring or a modified approach - elevated hematocrit for TRT, controlled hypertension for HRT, sleep apnea for testosterone therapy. Intake screens run both lists automatically. If your history triggers one, you'll get the reasoning and an alternative pathway - not a dead end.
Medically reviewed byDr. Lena Okafor, MD
Medical Director - updated April 2026How we review
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