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Glossary term
Serum bicarbonate
Also known as CO2 total
Serum bicarbonate is a biomarker used in cardiometabolic and preventive-health interpretation.
Serum bicarbonate is interpreted as part of a full biomarker pattern rather than in isolation. Trends over time and adjacent markers usually matter more than a single draw.
- Symbol
- HCO3-
- Unit
- mmol/L
Medically reviewed byDr. Lena Okafor, MD
Medical Director - updated April 2026How we review
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