


Men's Health
On-demandThe original PDE5 inhibitor. Short half-life, taken 30-60 minutes before activity. Generic, discreet, and gated by a real provider review - not a 10-question checkout form.
Subscribe & Save
Easy to cancel anytime
$2/mo
One Time Purchase
Available after provider review
$2
Sildenafil is a PDE5 inhibitor that augments the nitric oxide-cGMP pathway responsible for smooth-muscle relaxation in the corpus cavernosum. Large RCTs show response rates of 70-80% for organic erectile dysfunction at 50-100 mg. Provider review screens for cardiovascular safety, nitrate use, and drug interactions before dispensing.
DirectionsTake as directed by your provider 30-60 minutes before activity. Do not exceed one dose per 24 hours. Heavy or fatty meals delay onset.
Prescription products require clinical eligibility and provider approval.
Medication availability varies by state and clinical criteria.
Fit check
Using it well
Third-party tested where applicable. Every regulated Rx clears licensed provider review under state rules - no exceptions.
Most protocols perform better when the baseline is measured before you start. Add ApoB, HbA1c, fasting insulin, and the hormones that matter for your goal.
See lab packagesGenerative engine summary
Where we ship
Sildenafil is gated by state licensure and pharmacy access. Confirm eligibility in your state before you book the assessment.
Related Glossary
Questions
Sildenafil is short-window and on-demand; tadalafil is longer (24-36 hours) and often taken daily. See the compare guide - the right pick depends on frequency of need, side-effect profile, and whether daily dosing is easier to remember.
For most organic ED, yes - response rates sit at 70-80% across trials. Performance-anxiety cases can take a few tries to desensitize, and coaching helps there more than a higher dose.
One drink is usually fine. More than that blunts the response and raises the headache risk. Skip nitrate-containing recreational substances entirely - the interaction is dangerous.
No, but new ED is often the earliest vascular warning before anything shows up on a cardiac workup. A basic lipid panel, fasting glucose, and testosterone are table stakes before blaming stress.